Echinoderms, a group of marine invertebrates, can regenerate their arms and limbs. If it is possible to mimic echinoderms' physiological and regenerative abilities by using their extracellular vesicles, they are expected to become an important ingredient among marine medicines.
Sea cucumbers are a class of echinoderms, the Holothuroidea, and they can be found on the seabed.
Past studies have shown the biological activities of sea cucumber extracts as antimicrobial, anticancer and Immunomodulatory properties as well as wound healing stimulant.
Due to the fact that human skin is constantly exposed to various physical or chemical damages and skin wounds can cause appearance and functional abnormalities, a study was conducted on the effect of exosome derived from sea cucumber in the healing of skin wounds.
The results of this study demonstrated that extracellular vesicles can be used as a new and effective treatment for wound healing, especially in patients with impaired wound healing.
Also, due to the high regenerative ability of these creatures, this ability can be used in the production of skin products with anti-aging and anti-inflammatory properties.
The development of medicinal products based on Holothuroidea exosomes can contribute to improving the quality of life of patients with chronic wounds and reduce healthcare costs caused by the treatment of complex wounds.